Phenylpropanoids and polyketides
Matrix Scientific 4-CHLOROCINNAMIC ACID-25G
4-Chlorocinnamic acid, 99%; 25g,C9H7ClO2, MFCD00004396, mw 182.61, [1615-02-7]
Medchemexpress LLC PI3K/AKT-IN-1 | 3033069-84-7 | 99.6% | C23H23N5O4S | 25 MG
PI3K/AKT-IN-1 is an effective dual inhibitor of PI3K and AKT, exhibiting anticancer activity by inhibiting the PI3K/AKT axis and inducing caspase 3-dependent apoptosis. This compound has high cytotoxic activity against leukemia K562 and breast cancer MCF-7 cell lines, and is intended for research use only.
- Demonstrates high cytotoxic activity, particularly against leukemia cell line K562 (IC50=2.62 μM) and breast cancer cell line MCF-7 (IC50=3.22 μM)
- Promotes S-phase cell cycle arrest and induces apoptosis in K562 cells
- Significantly reduces the expression of PI3K, p-PI3K, AKT, p-AKT, Cyclin D1, and NF-κB
- Found to be non-toxic and well-tolerated in animal studies, with an LD50 greater than 2000 mg/kg
- Soluble in DMSO at 50 mg/mL
- Solid, off-white to light yellow appearance
Apexbio Technology LLC (-)-epicatechin 490-46-0 10mg
(-)-Epicatechin (CAS 490-46-0) is a flavonoid compound known for inducing pancreatic -cell regeneration and modulating nitric oxide (NO) metabolism It inhibits nitric oxide-related nitrite formation induced by interferon- and lipopolysaccharide in mouse macrophages and reduces peroxynitrite-mediated tyrosine nitration in HL-60 human leukemia cells Additionally in human endothelial cells (HUVECs) it enhances NO production displaying vasodilatory properties In diabetic rat models (alloxan-induced) (-)-epicatechin administration promotes -cell recovery reduces hyperglycemia and prevents -cell necrosis This profile underscores its research relevance for diabetes and vascular biology investigations
Medchemexpress LLC Oxytetracycline (hydrochloride) | 2058-46-0 | 98.9% | 1 G
Oxytetracycline hydrochloride is an antibiotic that belongs to the tetracycline class. It is a potent inhibitor of both Gram-negative and Gram-positive bacteria. This compound acts as a protein synthesis inhibitor by preventing the binding of aminoacyl-tRNA to the m-ribosomal RNA complex. Additionally, Oxytetracycline hydrochloride exhibits anti-HSV-1 activity. Oxytetracycline is a bacterial aromatic polyketide, synthesized by a type II polyketide synthase which generates its poly-beta-ketone backbone through successive decarboxylative condensation of malonyl-CoA extender units, followed by modifications from cyclases, oxygenases, transferases, and other tailoring enzymes.
- Antibiotic belonging to the tetracycline class
- Potent inhibitor of Gram-negative and Gram-positive bacteria
- Functions as a protein synthesis inhibitor
- Prevents aminoacyl-tRNA binding to the m-ribosomal RNA complex
- Possesses anti-HSV-1 activity
eMolecules 185040-35-1 | 4-Ethylamino-2-methanethiopyrimidine-5-carboxaldehyde | 1g
Ambeed | 4-Fluoro-5-methoxy-1H-indole | 100mg | 561133591 | A355562 | 288385-89-7 | MFCD12924604 | 165.167 | C9H8FNO
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STA PHARMACEUTICAL US LLC N-Fmoc-2,3-difluoro-D-phenylalanine | 25 g | CAS 1260609-30-0 | InChIKey MNEDJBJASVXQIC-OAQYLSRUSA-N
N-Fmoc-2,3-difluoro-D-phenylalanine is a Amino Acid reagent (Subcategory: Phe) sold by WuXi TIDES. Offered in 25 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 1260609-30-0
- MDL: No data
- InChIKey: MNEDJBJASVXQIC-OAQYLSRUSA-N
- Molecular Weight: 423.416
- Molecular Formula: C24H19F2NO4
- Purity: ≥95%
- Container Type: 125 mL HDPE
- Pack Size: 25 g
- Net Weight: 25 g
- Gross Weight: 54.3 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: (R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(2,3-difluorophenyl)propanoic acid
- SMILES: O=C(OCC1C2=CC=CC=C2C3=CC=CC=C31)N[C@@H](C(O)=O)CC4=CC=CC(F)=C4F
Cayman Chemical 3-HydroxycoumarIn 5g
A coumarin with diverse biological activities; inhibits 15-LO-1 (IC50 = 9.5 µM); scavenges DPPH radicals in a cell-free assay (IC50 = 0.61 mM); inhibits lipid peroxidation in vitro (IC50 = 69.07 mM); protective against UVB-induced embryotoxicity in sea urchins
Indofine Chemical Kaempferol, 99%, 100 Mg
KAEMPFEROL 100 MG, Flavone, 3,5,7,4'-Tetrahydroxyflavone; Robigenin, C15H10O6, MW: 286.24, 0.99, 520-18-3, MFCD00016938
eMolecules 56578-37-1 | Ambeed | (E)-3-Chlorocinnamaldehyde | 1g | 521474200 | A606962 | MFCD07437882 | 166.6 | C9H7ClO
Ambeed | (E)-3-Chlorocinnamaldehyde | 1g | 521474200 | A606962 | 56578-37-1 | MFCD07437882 | 166.600 | C9H7ClO